Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin
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منابع مشابه
Mutation at codon 442 in the rpoB gene of Mycobacterium leprae does not confer resistance to rifampicin.
BACKGROUND Rifampicin is the major drug in the treatment of leprosy. The rifampicin resistance of Mycobacterium leprae results from a mutation in the rpoB gene, encoding the β subunit of RNA polymerase. As M. leprae is a non-cultivable organism observation of its growth using mouse food-pad (MFP) is the only Gold Standard assay used for confirmation of "in-vivo" drug resistance. OBJECTIVE Any...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 2016
ISSN: 2162-8807
DOI: 10.47276/lr.87.1.93